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Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects

Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects

July 11, 2025 Category: Blog

Summary: Contraction of the human sarcomere is the result of interactions between myosin cross-bridges and actin filaments.Pathogenic variants in genes such as MYH7, TPM1, and TNNI3 that encode parts of the cardiac sarcomere cause muscle diseases that affect the heart, such as dilated cardiomyopathy and hypertrophic cardiomyopathy.In contrast, path

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Post-Asean Agreement on Transboundary Haze Pollution: How to Settle the Dispute Settlement?

July 11, 2025 Category: Blog

Forest fire happened several times in Indonesia which impacting neighboring countries, such as Malaysia and Singapore.ASEAN tried to "heal" and prevent the possibility of similar events by signing the ASEAN Agreement on Transboundary Haze Pollution (AATHP) for its members.In line with that, Wide Fireplace Insert this research examined the concern o

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